The micro-organisms may be harmful to some people with weakened immune systems or some lung conditions, according to the company.
Up to 11 other countries, including some where the product has a different brand name, are also involved in the recall of 300-mL containers containing chlorhexidine.
"The presence of micro-organisms has been detected in some retained production samples of Periogard," Colgate-Palmolive said in a statement. "Under certain circumstances, these micro-organisms may be harmful to individuals with compromised health. Accordingly, in order to ensure the safety of our consumers, in cooperation with the Medicine and Health Regulatory Authority, Colgate-Palmolive UK is recalling all Periogard."
No other Colgate mouthwash products are included in the recall, the company noted.
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